Sunday, July 5, 2009

Hydroboration Oxidation of Alkenes

Alkenes react with diborane (B2H6) and form trialkyl boranes.
Trialkylboranes then react with H2O2 and give alcohols.

Due to this reaction Propene is converted to alcohol

H3C-CH=CH2 is converted to H3C-CH2-CH2OH

The final result of this raction is the addition of a water molecule to the double bond of the molecule in a direction opposite to that of Markownikov rule.

This reaction was discovered by Herbert C. Brown, who was awared Nobel prize in 1980 for the synthetic use of the reaction.

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