Saturday, January 26, 2008

IIT JEE Revision Friedel-Crafts Acylation

Acylation is the term given to substituting an acyl group such as CH-3CO- into another molecule. An acyl group is a hydrocarbon group attached to a carbon-oxygen double bond.

The most commonly used example of an acyl group is the ethanoyl group, CH3CO-.

On treatment with an acid chloride (Acyl chloride) in the presence of anyhydrous aluminium chloride, acylation occurs.

Benzene + Acetyl chloride --> Acetophenone + HCl


The attacking electrophile an acyl carbocation RCO is supplied by acid chloride RCOCl in the presence of anhydrous AlCl3

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