Tuesday, February 5, 2008

Kolbe reaction Phenols

Kolbe's reaction

When sodium phenoxide is heated with carbon dioxide at about 400K and under 4 to 7 atmospheric pressure, sodium salicylate is formed as a major product. This on acidification gives salicylic acid. A small amount of para isomer is also obtained and if the temperature is allowed to rise above 410 K, the para isomer dominates.

No comments: